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                <text>In this poster we investigate that engineered phage (K1F-GFP-EGF) for any loss of lytic activity caused by mutation as well as using confocal microscope to investigate the mutant phage’s ability to be to internalised by two human cell lines: hCMEC and Fibroblasts which are targeted by K1 infection&#13;
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              <text>Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by persistent synovial inflammation, joint destruction, and pain. While immune mechanisms underlying RA are well established, emerging evidence highlights an important role for neuro-immune crosstalk in disease progression. In particular, mast cells and transient receptor potential (TRP) ion channels may contribute to inflammatory signalling within the synovium. This study aimed to genotype and characterise transgenic mouse models of RA to investigate the roles of mast cells and TRP channels, with a focus on TRPM2 and TRPM8.  Wild-type, heterozygous, conditional knockout, and global knockout mice were analysed. Genotyping was performed using PCR and agarose gel electrophoresis to confirm genotype. Histological analysis of mouse knee joints was conducted using haematoxylin and eosin staining to assess tissue morphology, toluidine blue staining to identify mast cells, and immunostaining to detect TRP ion channel expression. Protein analysis was performed using ELISA to quantify inflammatory mediators, including IL-6, PGE₂, and Substance P, alongside Bradford assays to determine total protein content.  PCR successfully confirmed the generation of transgenic mouse lines. Histological analysis revealed synovial inflammation and mast cell infiltration characteristic of RA, while immunostaining identified TRPM2 and TRPM8 expression within inflamed joints. TRPM2 knockout mice exhibited reduced inflammatory features compared to wild-type controls. ELISA confirmed the presence of key inflammatory mediators, supporting a mechanistic link between neuronal signalling and mast cell-driven inflammation. Collectively, these findings support a contributory role for mast cells and TRP ion channels in RA pathology and highlight their potential as therapeutic targets.</text>
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              <text> In many modern physics and engineering systems, particularly when dealing with separable linear partial differential equations, a second- order linear ordinary differential equation in a certain form occurs fre- quently, these are called Sturm-Liouville problems. Understanding the solutions in such a form is crucial in understanding a dynamic system when Sturm-Liouville problems occur. We will embark on an in-depth exploration of Riemannian geometry, uncovering the rich properties provided by the Riemannian metric. By the end, we’ll bring everything together and demonstrate how tools from Sturm-Liouville theory can be applied to specific geometric surfaces.</text>
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              <text>Investigating the socio-cultural dynamics: How do the post-World War II experiences of German Ghanaians influence their integration into German society, and what role does the phenomenon of double consciousness play in shaping the identity of the third generation within the German Ghanaian community? My research is motivated by the story of the generation of Ghanaians who migrated to Germany post WWII and also motivated by a need to understand and demonstrate how these individuals in the diaspora integrated and developed their identities in contemporary society.  </text>
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              <text>Despite its value, historical literature utilising the recently released government correspondence relating to the 1984-85 miners’ strike has been sparse. Sustained attention on how the government managed Media and PR in the strike has been even more limited. This essay seeks to make a novel contribution to the historiography of the strike by highlighting the Thatcher government’s media tactics during the most notorious British industrial dispute in living memory. It will do so by drawing heavily on primary material released in 2014, as well as existing literature on the broader government strategy in 1984-85.</text>
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              <text>Electron scattering can be simulated using the eigenstate (Bloch wave) method. This method, first developed by Hans Bethe in 1928, uses Bloch’s Theorem to solve the Schrödinger equation to find the eigensolutions of the equation.  The computation of this method involves the diagonalisation of a large matrix to get an eigenspectrum matrix of complex amplitudes. &#13;
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