Investigating the formation of the extra-embryonic yolk syncytial layer (YSL) in zebrafish embryos

Title

Investigating the formation of the extra-embryonic yolk syncytial layer (YSL) in zebrafish embryos

Subject

Life Sciences

Creator

Abigail Wimshurst

Date

2025

Contributor

Karuna Sampath

Abstract

Extra-embryonic tissues assist development but aren’t part of the embryo body, for example zebrafish YSL and mammalian placentas. Zebrafish YSLs form during early cell divisions when membranes of marginal blastomeres retract, forming a multinucleated layer. YSLs can grow abnormally, associated with specific gene defects. Studying what causes these defects to arise during YSL development can aid understanding of healthy embryonic development, and could be used as a model organism to better understand mammalian development.

Meta Tags

zebrafish, YSL, foxj1a, micall2a, immunostaining, WISH, biology, embryo

Files

Citation

Abigail Wimshurst, “Investigating the formation of the extra-embryonic yolk syncytial layer (YSL) in zebrafish embryos,” URSS SHOWCASE, accessed November 4, 2025, https://linen-dog.lnx.warwick.ac.uk/items/show/972.